Sedating antihistamines for children
If you are desperate (and still coughing and sneezing and itching), you may be tempted to take too much.
BUT - it can be dangerous to take extra antihistamines. online tool for guidance or call Poison Control right away at 1-800-222-1222.
Whether you use the online tool or call, you'll be able to determine if treatment is needed.
Serkalem Mekonnen, RN, BSN, MPH Certified Specialist in Poison Information Case 1: A 13-month-old 22-lb boy was discovered by his mom playing with an empty bottle of Unisom® gelcaps (diphenhydramine 25 mg).
About 3.5 hours after he was found with the medication bottle, he began having frequent seizures and developed a very fast heart rate and an abnormal heart rhythm.
Topical preparations (ointments and creams) are often applied to insect bites but are not very effective as the antihistamine chemical does not penetrate the skin well.
He was discharged to home without any further problems on hospital day 4.
This means it has an effect on small blood vessels, resulting in dilated capillaries (redness), and leakage of protein-rich fluid into surrounding skin (swelling).
Because of the particular hospital's experience treating an adult patient with a diphenhydramine overdose with hemodialysis (blood flows through a special filter that removes poisons, and the clean blood is returned to the body), a team of physicians, including a toxicologist, decided that hemodialysis was a reasonable life-saving option for this small child. After the first, his seizures and abnormal heart rhythm resolved, though his heart rate was still slightly fast. Though the 25 mg total dose of diphenhydramine was more than he needed for his allergies, it was not enough to cause a serious problem based on his age and weight.
After a second hemodialysis treatment, he was stable. Poison Control recommended giving him fluids to drink and observing at home. Case 3: An adult male was prescribed hydroxyzine (Atarax®), an antihistamine that causes drowsiness, to help him sleep.Because they are broken down by the liver, those with liver disease are best to take a reduced dose as there will be excessive levels circulating in the blood stream.